Detailed Notes on Dimas Avila Review
Title: Respuesta inmune humoral contra el epitopo alfa-galactosil en pacientes con neoplasia intraepitelial cervical.
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Anti-Gal es un anticuerpo normal policlonal que interactua con un gluconjugado no expresado en celulas humanas. En condiciones fisiologicas especiales y en infecciones por kinetoplastidos anti-gal asume un rol protector. Evidencias senalan que este anticuerpo y otros relacionados como el que reacciona contra el residuo glucosidico Gal (& 1-two) Gal, forman parte del sistema de vigilancia antitumoral. La finalidad de este estudio fue confirmar que pacientes con carcinoma in situ de cuello uterino (NIC three) tienen niveles sericos anormalmente elevados de estos anticuerpos, comparar estos niveles a los de pacientes con lesiones mas tempranas (infeccion por virus de papiloma humano, NIC 1 y NIC two) y estudiar si el editopo se expresa en las celulas atipicas.
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